Speaker
Description
Optical tweezers are a sterile, non-invasive method for the isolating and manipulating single cells in suspension. When combined with microfluidic sample chambers it is possible to control the local environment of a trapped cell. This control over the extracellular environment of individual cells, allows one to monitor changes in cellular activity and cell morphology due to changes in the surrounding environment.
In this poster, we present an overview of a custom multimodal microscope integrated with optical tweezers (biophotonics platform), which has been constructed and used to monitor changes in the morphology and metabolic activity of single yeast cells under various cell stress environments. The poster also includes a brief descriptions of holographic optical tweezers (HOT), which uses a spatial light modulator to shape the optical field used to trap multiple cells, and optical quadrature microscopy (OQM), a quantitative phase imaging (QPI) technique used to image the phase variations within a trapped cell.
| Apply for student award at which level: | PhD |
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| Consent on use of personal information: Abstract Submission | Yes, I ACCEPT |